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Because several closely related subspecies of Treponema pallidum existed throughout Europe, it is possible that the diseases persisted in overlapping regions, and sometimes infected the same patient.
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The spatial distribution in the northern periphery of Europe also suggests that endemic treponematoses had already spread widely in Europe in the early modern period. The genetic analyses conducted in this study suggest that the predecessor of all modern Treponema pallidum subspecies likely evolved at least 2, years ago. For venereal syphilis in particular, the latest common ancestor existed between the 12th and 16th century.
According to the newly discovered diversity of treponematoses in early modern Europe, syphilis may have either originated or perhaps further developed in the Old World. We may yet have to revise our theories about the origins of syphilis and other treponemal diseases.
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Materials provided by University of Zurich. Note: Content may be edited for style and length. Science News. Yaws already widespread in Europe The new study indicates a fair possibility that Treponema pallidum already existed in Europe before Columbus ever set sails to America. Genome of a previously unknown pathogen discovered The research team also discovered something else: The skeleton found in the Netherlands contained a pathogen belonging to a new, unknown and basal treponemal lineage.
Story Source: Materials provided by University of Zurich. Current Biology , ; DOI: ScienceDaily, 13 August University of Zurich. Syphilis may have spread through Europe before Columbus. Retrieved October 10, from www. The change alters a protein on its cell surface to create a distraction.
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